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. 2021 Apr 11;18(8):4006. doi: 10.3390/ijerph18084006

Table A1.

Main characteristics of the studies reviewed: authors, sample size, gender distribution, age range, mean age, sample characteristics, and task information (n = 19).

Ref. Sample Size Groups Gender Distribution Age Range and Mean Age (SD) Sample Characteristics Task Information (and Duration if Available)
[14] 3 1 experimental group NR NR Children with diagnosis of autism Labyrinth game: item manipulation task
[15] 12 2 groups
Control group: 6 participants organized in 3 TD/TD couples
Experimental group: 6 participants organized in 3 ASD/TD couples
83% male Range = NR
Control group: Mage = 9.99 (0.87)
Experimental group:
Mage ASD = 11.70 (2.24);
Mage TD = 11.09 (1.19)
Children with ASD and typically developing children Collaborative games: puzzle, collection, delivery games (5 min playtime in pre-test; less than 5 min in post-test)
[16] 24 2 groups
Control group:
6 ASD/TD couples
Experimental group: 6 ASD/TD couples
NR Control group:
Range = NR
Mage ASD = 12.38 (2.60); Mage TD = 12.60 (2.66);
Experimental group: Mage ASD = 12.12 (3.59);
Mage TD = 13.15 (3.77)
Children with ASD and typically developing children Collaborative games: puzzle, collection, delivery games
[23] 60 2 groups
Control group: 37 cognitively intact participants;
Experimental group:
23 cognitively impaired participants
Control group: 70.3% female;
Experimental group: 65.2% female
Range = 65–85;
Group 1: Mage = 70.7 (3.6);
Group 2: Mage = 73.2 (5.4)
Elderly with and without cognitive impairment from a public primary care clinic in Singapore Activities of daily living: opening door with correct key and passcode number; making a phone call recalling a number; identifying items from different categories in a newspaper; sorting things in a room; picking appropriate outfit for occasion; withdrawing cash from automated teller machine; shopping at provision shop
(Average time to complete the task of 19.1 min (3.6) in control group; average time of 20.4 (3.4) time in experimental group)
[34] 20 2 groups
Control group:
10 healthy children
Experimental group:
10 children with ADHD
Group 1: 60% male;
Group 2: 60% male
Range = 7–12;
Mage = NR
Children with and without ADHD Matching game: color-matching association of geometric figures and boxes
(Three attempts in a week, average time of 16.56 min in experimental group; average time of 13.54 min in control group)
[35] 3 (Multiple probe design across participants) 100% male Range = 6–7
Mage = NR
First-grade students diagnosed with ASD (1 in mild and 2 in moderate range) from an elementary school in Beijing Match-to-sample task
(20 pre-experimental training trials per session every day, 10–15 min each session. Five seconds to provide response in the intervention phase)
[36] 4 1 experimental group
(Adapted alternating treatment design. Two conditions—CAI and TII—were alternated with each student each day)
75% male Range = 9–11;
Mage = NR
Fourth-grade students with different diagnosis (2 severe autism and mild intellectual disability, 1 Down’s syndrome and mild intellectual disability, 1 moderate intellectual disability) from a Chinese special education school Match-to-sample task
(20 pre-experimental training trials for each condition, 10–15 min each session. Five seconds to provide response in the intervention phase)
[37] 3 (Single subject research design) 66.66% male Range = 9–11;
Mage = NR
Students with severe autism from a special needs school in Beijing Matching game: color-matching balls to boxes and fruits to sticks
(Three-week experiment, half an hour a day for five days a week)
[38] 2 Single subject research design 50% male Range = 9–10;
Mage = NR
Third-grade students with severe autism from a special school in Beijing Matching game: color-matching balls to boxes and fruits to sticks
(30 min every day)
[39] Study 1: 5 (+ parents)
Study 2: 5 (+ teachers)
1 experimental group for each of the two studies 100% male Range = NR;
Study 1:
Mage = 4.8 (1.8);
Study 2:
Range = NR;
Mage = 6.3 (2.4)
Study 1: Children with diagnosis of autism and their family members;
Study 2: Children with diagnosis of autism;
They all came from a Chinese Children’s Educational Development Center
Drawing game (playtime of 15 min);
Word-image pairing in zoo and home interactive game
[40] Study 1: 5 (+ parents)
Study 2: 5
(+ teachers)
Study 3: 9
1 experimental group for each of the two studies Study 1, 2 = 100% male
Study 3: 55.5% male
Range = NR;
Study 1:
Mage = 4.8 (1.8);
Study 2:
Range = NR;
Mage = 6.3 (2.4);
Study 3:
Mage = 8.1 (3.4)
Study 1: Children with diagnosis of autism and their family members;
Study 2: Children with diagnosis of autism;
Study 3: Children with diagnosis of autism (1 also with ADHD, 5 with highly functioning ASD, 4 with low functioning ASD)
Drawing game (15 min of play);
Word-image pairing in zoo and home interactive game;
Drum playing game
[41] 2 2 groups
Experimental group 1: 1
Experimental group 2: 1
NR NR Participants with similar characteristics as children with autism (1 with better motor skills but focus issues; 1 with motor impairment) Matching games;
Sign recognition task;
Eye gazing task
(Three sessions of training for each game)
[42] NR 1 experimental group NR Range = 9–12;
Mage = NR
Typically developing children Avatar greeting task
(Two sessions, 20 min per session)
[43] 10 1 experimental group
(Virtual-based and performance-based assessment were done on each participant in parallel)
NR NR Healthy adults without diagnosis of cognitive impairment Lunch box packing task
[44] 16 1 experimental group 68.7% male Range = 65–72 Mage = 68 (2.76) Elderly without experience in playing video games from a University Hospital in Tokyo (NR diagnosis) Table preparation task
[45] NR NR NR NR NR Shopping task
[46] 223 Control group: 71
Experimental group 1: 65
Experimental group 2: 42
Experimental group 3: 45
56% female Range = NR;
Mage = 72.73 (6.89)
Elderly people from two Alzheimer day clinics in Greece (71 healthy elderly, 65 elderly with amnestic single-domain MCI, 42 elderly with amnestic multi-domain MCI, 45 elderly with mild Alzheimer’s dementia) Finger-tapping test in in a fire evacuation task
(As fast as user could for 15 s)
[47] 205 Control group: 72
Experimental group 1: 65
Experimental group 2: 68
57% female Range = NR
Mage = 72.73 (6.89)
Elderly people from two Alzheimer day clinics in Greece (72 healthy elderly, 65 elderly with amnestic MCI, 68 elderly with mild Alzheimer’s disease) Finger-tapping test in a fire evacuation task
(As fast as user could for 15 s)
[48] 19 1 experimental group 66.7% male Range = NR
Mage = 10.88 (3.14)
Children (NR diagnosis) Mathematical operations

Note: NR = not reported; ADHD = attention-deficit hyperactivity disorder; ASD = autism spectrum disorder; CAI = computer-assisted instruction; TII = teacher-implemented instruction; MCI = mild cognitive impairment; TD = typically developing.