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(A) Overview of UCH-L1 structure (PDB ID: 3kw5) with ubiquitin (purple), ubiquitin binding sites (red), and catalytic triad (yellow). (B) UCH-L1 active site (dark grey ribbon and yellow sticks) superimposed on PLpro active site (light grey ribbon and green sticks) from PDB structures 3kw5 and 7jn2, respectively.
