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. 2021 Apr 11;26(8):2201. doi: 10.3390/molecules26082201

Table 2.

Most relevant radiotracers tested in clinical trials.

Targeting Molecule Agent Molecule Type Tumor Model Stage Reference
PD-L1 [18F]BMS-986192 adnectin NSCLC patients clinical [60]
[89Zr]-labeled atezolizumab antibody IgG1 metastatic bladder cancer, NSCLC, or triple-negative breast cancer clinical [61]
PD-1 [89Zr]nivolumab antibody IgG4 NSCLC patients clinical [60]
CD8+ [89Zr]Df-IAB22M2C minibody melanoma, lung cancer, and hepatocellular carcinoma clinical [62]