Table 2.
Targeting Molecule | Agent | Molecule Type | Tumor Model | Stage | Reference |
---|---|---|---|---|---|
PD-L1 | [18F]BMS-986192 | adnectin | NSCLC patients | clinical | [60] |
[89Zr]-labeled atezolizumab | antibody IgG1 | metastatic bladder cancer, NSCLC, or triple-negative breast cancer | clinical | [61] | |
PD-1 | [89Zr]nivolumab | antibody IgG4 | NSCLC patients | clinical | [60] |
CD8+ | [89Zr]Df-IAB22M2C | minibody | melanoma, lung cancer, and hepatocellular carcinoma | clinical | [62] |