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Pharmacological comparison of cis and trans pairs in both D3R and D2R mediated G protein activation and β-arrestin recruitment at 10 min. CRCs of AB04-87 (a), AB04-88 (b), AB04-95 (c) and AB04-96 (d)-induced BRET at 10 min between Gαo-RLuc and Gγ-Venus and D3R or D2R-Rluc and β-arrestin2-Venus. CRCs are plotted as percentage of maximal response by quinpirole and presented as means ± SEM of n ≥ 3 independent experiments.
