| ABC | ATP-binding cassette |
| API | application programming interface |
| ATP | adenosine triphosphate |
| BiGG | Biochemically, Genetically, and Genomically structured |
| BLAST | Basic Local Alignment Search Tool |
| BOF | biomass objective function |
| CDS | coding domain sequence |
| CF | cystic fibrosis |
| COBRA | Constraint-Based Reconstruction and Analysis |
| CTP | cytidine triphosphate |
| dATP | deoxyadenosine triphosphate |
| dCTP | deoxycytidine triphosphate |
| dGTP | deoxyguanosine triphosphate |
| dTTP | deoxythymidine triphosphate |
| EC | Enzyme Commission |
| ECF | energy-coupling factor |
| ECO | Evidence and Conclusion Ontology |
| FBA | flux balance analysis |
| fbc | flux balance constraints |
| FVA | flux variability analysis |
| GEM | genome-scale metabolic model |
| GPR | gene–protein reaction |
| GTP | guanosine triphosphate |
| HMDB | Human Metabolome Database |
| ID | identifier |
| ITP | inosine triphosphate |
| KEGG | Kyoto Encyclopedia of Genes and Genomes |
| MIRIAM | Minimal Information Requested in the Annotation of Models |
| NADH | reduced nicotinamide adenine dinucleotide |
| NADPH | reduced nicotinamide adenine dinucleotide phosphat |
| NCBI | National Center for Biotechnology Information |
| REST | representational state transfer |
| SBO | Systems Biology Ontology |
| SCFM | synthetic cystic fibrosis medium |
| SNM | synthetic nasal medium |
| URT | upper respiratory tract |
| UTP | uridine triphosphate |
| TCA | tricarboxylic acid |
| VMH | Virtual Metabolic Human |