Table 1.
Age distribution and boundaries (Q1 to Q3) for its partition in quartiles.
| Groups (1) | Gender | N (%) | Minimum | Q1 | Q2 | Mean | Q3 | Maximum |
|---|---|---|---|---|---|---|---|---|
| HC | Male | 19 (47.50%) | 24.00 | 26.00 | 32.00 | 36.58 | 40.50 | 71.00 |
| Female | 21 (52.50%) | 27.00 | 30.00 | 38.00 | 37.95 | 43.00 | 52.00 | |
| Total | 40 | 24.00 | 29.00 | 35.00 | 37.30 | 42.25 | 71.00 | |
| MS | Male | 14 (31.11%) | 24.00 | 31.25 | 39.00 | 41.21 | 49.50 | 63.00 |
| Female | 31 (68.89%) | 22.00 | 34.50 | 45.00 | 43.32 | 50.50 | 69.00 | |
| Total | 45 | 22.00 | 33.00 | 45.00 | 42.67 | 50.00 | 69.00 | |
| Diagnosis (2) | Gender | N (%) | Minimum | Q1 | Q2 | Mean | Q3 | Maximum |
| RRMS | Male | 12 (31.58%) | 24.00 | 31.00 | 33.50 | 38.42 | 47.25 | 58.00 |
| Female | 26 (68.42%) | 22.00 | 33.75 | 45.00 | 43.23 | 50.75 | 69.00 | |
| Total | 38 | 22.00 | 32.25 | 43.50 | 41.71 | 50.00 | 69.00 | |
| SPMS | Male | 2 (28.57%) | 53.00 | 55.50 | 58.00 | 58.00 | 60.50 | 63.00 |
| Female | 5 (71.43%) | 30.00 | 43.00 | 46.00 | 43.80 | 48.00 | 52.00 | |
| Total | 7 | 30.00 | 44.50 | 48.00 | 47.86 | 52.50 | 63.00 | |
| EDSS (3) | Gender | N (%) | Minimum | Q1 | Q2 | Mean | Q3 | Maximum |
| 0.5–3.0 | Male | 10 (31.25%) | 24.00 | 31.00 | 32.50 | 35.90 | 43.75 | 50.00 |
| Female | 22 (68.75%) | 22.00 | 33.00 | 42.00 | 41.50 | 50.00 | 69.00 | |
| Total | 32 | 22.00 | 31.00 | 38.00 | 39.75 | 49.25 | 69.00 | |
| 3.5–7.0 | Male | 4 (30.77%) | 44.00 | 50.75 | 55.50 | 54.50 | 59.25 | 63.00 |
| Female | 9 (69.23%) | 30.00 | 45.00 | 48.00 | 47.78 | 52.00 | 59.00 | |
| Total | 13 | 30.00 | 45.00 | 52.00 | 49.85 | 55.00 | 63.00 | |
| Disease onset (4) | Gender | N (%) | Minimum | Q1 | Q2 | Mean | Q3 | Maximum |
| ≤10 years | Male | 10 (37.04%) | 29.00 | 31.25 | 33.50 | 39.30 | 47.75 | 58.00 |
| Female | 17 (62.96%) | 22.00 | 30.00 | 39.00 | 40.59 | 52.00 | 59.00 | |
| Total | 27 | 22.00 | 30.50 | 37.00 | 40.11 | 50.50 | 59.00 | |
| >10 years | Male | 4 (22.22%) | 24.00 | 39.00 | 48.50 | 46.00 | 55.50 | 63.00 |
| Female | 14 (77.78%) | 33.00 | 43.50 | 46.00 | 46.64 | 49.75 | 69.00 | |
| Total | 18 | 24.00 | 43.25 | 46.00 | 46.50 | 50.00 | 69.00 | |
| Therapy (5) | Gender | N (%) | Minimum | Q1 | Q2 | Mean | Q3 | Maximum |
| No | Male | 2 (28.57%) | 32.00 | 39.75 | 47.50 | 47.50 | 55.25 | 63.00 |
| Female | 5 (71.43%) | 30.00 | 36.00 | 39.00 | 43.80 | 45.00 | 69.00 | |
| Total | 7 | 30.00 | 34.00 | 39.00 | 44.86 | 54.00 | 69.00 | |
| Yes | Male | 12 (31.58%) | 24.00 | 31.00 | 39.00 | 40.17 | 48.50 | 58.00 |
| Female | 26 (68.42%) | 22.00 | 34.00 | 46.00 | 43.23 | 50.75 | 59.00 | |
| Total | 38 | 22.00 | 33.00 | 45.50 | 42.26 | 50.00 | 59.00 |
(1): Healthy control (HC) or multiple sclerosis (MS). (2): MS patients with relapsing–remitting clinical form of MS (RRMS) and secondary progressive (SPMS) diagnosis. (3): MS patients, either with mild (expanded disability status scale (EDSS) = 0.5–3.0) or moderate/severe disability (EDSS = 3.5–7.0). (4): MS patients with short (≤ 10 years) and long (>10 years) time from the onset of the disease. (5): MS patients with (Yes) and without (No) therapy.