| Depressive disorder |
Elevated rate of women with endometriosis complaining of depressive symptoms, especially those with chronic pelvic pain (CPP) High risk for social, working and functional impairment Marital status has a protective effect Negative correlation with sexual satisfaction Risk of misinterpretation depressive symptoms and consequently setting up an incorrect therapy Psychopharmacological and psychotherapeutic treatment have a positive impact on quality life, pain management and overall outcome
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| Bipolar disorder |
Women with endometriosis have a reactivity to stressors with elevated risk of mood swings The high affective instability reduces the social and working functioning, and quality of life Strongly underestimated and underdiagnosed Mood stabilizers as a fundamental key for a positive overall outcome Not appropriate treatment could cause an acceleration of cycle frequency and an increase of the suicidality High risk of developing a comorbid substance use disorder (licit or illicit substances) Greater attention in the administration of hormone therapy
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| Anxiety and panic-agoraphobic spectrum disorders |
High prevalence of endometriotic patients to present anxiety fluctuations and symptoms of the anxious and panic-agoraphobic spectrum Women with endometriosis and CPP have a greater perceived stress Anxiety levels are strictly related to quality of life, to the presence of pain and to the severity of depressive symptoms Little data about psychotherapy and psychopharmacological treatment High risk of “central sensitization” of pain Risk of develop substance use disorder as a consequence of self-medication drug treatment (Benzodiazepines (BDZs), alcohol, cannabinoids, opioid)
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| Temperamental and personality traits |
Identification of personological profile: anxious or inhibited behavior, insecurity in acting, low self-esteem, affective or decision-making dependence, fear of separation, catastrophizing, tendency towards control and perfectionism Struggle in pain management and risk of “central sensitization” Negative reinforces towards thoughts/beliefs and feeling of powerlessness leading to psychological distress Risk of comorbid affective and/or anxiety disorders Risk of comorbid substance use disorder
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| Substance use disorder |
Worsening of the psychopathological conditions and reduced possibilities to manage the pharmacological treatment Worsening of the pain management Worsening of the sexual satisfaction Risk of relationship problems Reduction of social and working performances High economic expanses Risk of presenting maladaptive behaviors
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