Table 2.
Involvement of lncRNAs in osteoclastogenesis.
| Sources | lncRNAs | Regulation Mechanism | Potential Role in Osteoclastogenesis | Study |
|---|---|---|---|---|
| EPC-derived exosomes | MALAT1 | Sponging miR-124 (ITGB1) | Regulates osteoclast migration and differentiation | [72] |
| Cells | DANCR | Regulates Jagged1 and RANKL expression | Regulates osteoclast formation | [73] |
| Cells | NEAT1 | Sponging miR-7 (PTK2) | Regulates osteoclast formation | [78] |
| Cells | TUG1 | Regulates V-MafB | Regulates osteoclast differentiation | [79] |
| Cells and animals | MIRG | Sponging miR-1897 (NFATC1) | Regulates osteoclast formation | [80] |
| Cells | Bmncr | Downregulates osteoclast-related marker genes | Regulates osteoclast differentiation | [81] |
| Cells and animals | NRON | Regulates NFATC1 expression | Regulates osteoclastogenesis during orthodontic bone resorption | [82] |
| Bioinformatic analysis | RP11-498C9.17 | Regulates genes mainly enriched in pathways regulating bone mineral density | Regulates osteoclastogenesis | [83] |
| Bioinformatic analysis | ENSG00000257764.2 | Sponging miR-106a-5p (TIMP2) | Regulates osteoclast differentiation | [84] |