Table 4.
Markers that exhibit a statistically significant relationship with respect to TNM classification.
| Biomarker | Mean Ratio [95% CI) | ||
|---|---|---|---|
| TNM ª | |||
| 2 | 3 | 4 | |
| Ki67 stroma | 0.99 (0.75–1.32) |
1.09 (0.79–1.51) |
0.72 * (0.57–0.92) |
| HF1beta epithelium | 0.49 (0.22–1.12) |
0.18 * (0.07–0.46) |
0.37 * (0.18–0.74) |
| VEGF epithelium | 1.29 (0.63–2.66) |
0.95 (0.42–2.15) |
0.45 * (0.24–0.83) |
| VEGF lymphocytes | 0.87 (0.54–1.41) |
2.27 * (1.33–3.88) |
1.16 (0.78–1.74) |
| MMP9 macrophages | 1.27 (0.61–2.66) |
3.29 * (1.42–7.63) |
1.93 * (1.02–3.63) |
ª reference level TNM 1; * p < 0.05 (presented in bold); adjusted by age and gender.