Figure 1.

Stages of wound infection and corresponding clinical symptoms [9,10,12]. * antisepsis, wound debridement, antimicrobial dressings, non-antibiotic local treatment. Local antibiotic therapy is not recommended. ** systemic empiric antibiotic therapy depends on the clinical condition of the patient. Empirical treatment should consider the expected pathogens, the site and nature of the infection, and cover the broadest possible spectrum of microorganisms. Empirical antibiotic therapy should be turned into targeted antibiotic therapy as soon as possible after obtaining microbiology test results.