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. 2021 Apr 13;10(8):1659. doi: 10.3390/jcm10081659

Table 1.

PICOS criteria for inclusion and exclusion of studies.

Parameter Defined criteria for the current study
P (population) Adult patients with MAFLD
I (intervention) Aerobic exercise
C (comparison) Usual care or another type of intervention
O (outcomes) Primary: changes in serum levels of liver enzymes, intrahepatic triglycerides
Secondary: glucose metabolism, anthropometric changes
S (study design) Randomized clinical trials