Table 2.

Various health implications of COVID-19 infections [3].

Sl No	Organ system involved	Severe Disease	Diagnostic Signs
1	Blood vessels/Vascular	•Pulmonary embolism •Large vessel occlusions •Disseminated intravascular coagulation	•Elevated D-dimer, •interleukin-6, other cytokines, ferritin, and lactate dehydrogenase Prolonged PT/PTT
2	Lung/Respiratory- Pulmonary	•Severe hypoxemia •Acute respiratory distress syndrome (ARDS) •Respiratory failure and death (if untreated)	•Decreased % pO2 •Chest X-rays show •Ground glass obacities
3	Gastrointestinal	•Gastrointestinal bleeding •GI viral dissemination	•Elevated liver enzymes andbilirubins •SARS-CoV-2 detection in stoolsamples
4	Brain/Neurological	•Cerebrovascular disease(large vessel strokes) •Seizures •Meningoencephalitis •Neuropathy •Guillain Barre Syndrome •Neurogenic ARDS •Coma	•Elevated creatine kinase with myalgia •Brain MRI show hyperintensitiesin regions with infarction or encephalitis •SARS-CoV-2 detection incerebrospinal fluid or brain tissues in some patients
5	Kidney/Renal	•Renal failure	•Tubular necrosis and SARS-CoV-2 detection in kidney
6	Heart/Cardiac	•Cardiomyopathy •Acute heart failure	•Elevated cardiac enzymes •Abnormal EKG (Prolonged QTcintervals, elevated ST) •Cardiac-specific troponin and brain natriuretic peptide
7	Mental/Psychiatric	•Exacerbation of neurological orpsychiatric disorders (e.g., Alzheimer's or Addiction)	•Elevated plasma calcium and phosphorus (indicative of stress)