Age, median (IQR) |
59 (18.0) |
59 (20) |
0.893 |
<60 years % |
45.8 |
50.8 |
|
≥60 years % |
55.2 |
49.2 |
|
Gender, % |
|
|
0.564 |
Female |
32.2 |
37.3 |
|
Male |
67.8 |
62.7 |
|
Comorbidities, % |
61.0 |
62.7 |
0.393 |
Diabetes |
19.3 |
28.3 |
0.269 |
Arterial hypertension |
29.8 |
37.7 |
0.382 |
Coronary artery disease |
7.0 |
13.2 |
0.282 |
Heart failure |
3.5 |
9.4 |
0.205 |
Pulmonary disease |
14.0 |
9.4 |
0.457 |
Renal impairment |
8.8 |
11.3 |
0.276 |
Solid tumor |
1.8 |
7.5 |
0.658 |
Hematological malignancy |
3.5 |
1.9 |
0.603 |
Symptoms, % |
|
|
|
Fever |
98.2 |
96.6 |
0.571 |
Myalgia |
8.8 |
10.3 |
0.775 |
Cough |
56.1 |
48.3 |
0.401 |
Dyspnea |
36.8 |
53.4 |
0.08 |
Loss of taste |
8.8 |
3.4 |
0.235 |
Anosmia |
5.3 |
5.2 |
0.983 |
Diarrhea |
19.3 |
19.0 |
0.964 |
Baseline laboratory parameters, median (IQR) |
|
|
|
Lymphocytes, (109/L, NR: 1.1–4.0) |
1.17 (0.7) |
1.02 (0.6) |
0.207 |
Platelets, (109/L, NR: 130–400) |
196 (101.5) |
197 (75.3) |
0.721 |
CRP, (mg/L, NR: 0.00–6.00) |
47 (50.3) |
44.8 (71.9) |
0.772 |
Fibrinogen, (mg/dL, NR: 200–400) |
485 (173) |
477 (253.9) |
0.631 |
LDH, (U/L, NR: 135–225) |
315 (167.8) |
277 (127.3) |
0.165 |
Ferritin, (ng/mL, NR: 13–150) |
597 (451.5) |
474 (167.9) |
0.443 |
Intereukin-6, (pg/mL, NR: <7) |
30.5 (43.6) |
|
|
SARS-CoV-2 PCR CT value |
26.8 (6.9) |
27.5 (9.3) |
0.700 |
Percentage of infiltrates at baseline CT, % |
|
|
0.117 |
<25 |
29.1 |
39.6 |
|
25–50 |
38.2 |
43.8 |
|
50–75 |
25.5 |
8.3 |
|
≥75% |
7.3 |
8.3 |
|
Concomitant dexamethasone, % |
59.3 |
49.2 |
0.270 |
Baseline SOFA score |
5 (4) |
4 (4) |
0.295 |
Time from first symptom to diagnosis, median (IQR) |
3 (4] |
4 (3) |
0.265 |
Time from first symptom to CP infusion, median (IQR) |
7 (4) |
|
|
Time from diagnosis to CP infusion, median (IQR) |
3 (3) |
|
|