Table 4.
Results of multivariate Cox regression analysis for the association between the convalescent plasma infusion and the antibody levels in the infused plasma and overall survival.
| Variables | HR (95%CI) | p-Value 1 |
|---|---|---|
| Age | 1.04 (0.97–1.12) | 0.233 |
| Percentage of infiltrates at CT | 3.87 (1.56–9.58) | 0.003 |
| Convalescent plasma infusion | 0.04 (0.004–0.36) | 0.005 |
| Subgroup analyses by level of plasma antibodies (cut -off: median) 2 | ||
| N_RBD (In-house ELISA), below median | 0.08 (0.006–1.09) | 0.059 |
| N_RBD (In-house ELISA), above median | 0.02 (0.001–0.34) | 0.007 |
| Spike (In-house ELISA), below median | 0.10 (0.008–1.21) | 0.070 |
| Spike (In-house ELISA), above median | 0.02 (0.001–0.33) | 0.007 |
| Spike_RBD (In-house ELISA), below median | 0.08 (0.007–1.003) | 0.051 |
| Spike_RBD (In-house ELISA), above median | 0.02 (0.001–0.35) | 0.008 |
| ID50, below median | 0.14 (0.01–1.91) | 0.139 |
| ID50, above median | 0.02 (0.001–0.29) | 0.016 |
1 Highlighted (bold) p-values denote statistically significant results; 2 Reference category: no plasma infusion.