Table 1.
Experimental design for DPE-NE formulations and their corresponding observed values of response.
| Formula | Independent Variables | Response Values | |||
|---|---|---|---|---|---|
| A (g) | B (g) | Y1 (nm) |
Y2 (%) |
Y3 (%) |
|
| F1 | 0.2 | 2 | 225 | 45.4 | 3.5 |
| F2 | 0.6 | 2 | 200 | 46.5 | 6 |
| F3 | 0.68 | 1.5 | 150 | 62.8 | 6.2 |
| F4 | 0.2 | 1 | 142 | 67.6 | 3.3 |
| F5 | 0.11 | 1.5 | 175 | 61.9 | 2.4 |
| F6 | 0.4 | 0.79 | 125 | 74.7 | 4.6 |
| F7 | 0.4 | 1.5 | 170 | 58.2 | 4.8 |
| F8 | 0.4 | 1.5 | 166 | 60.8 | 5 |
| F9 | 0.6 | 1 | 130 | 70.8 | 5.8 |
| F10 | 0.4 | 1.5 | 168 | 58.6 | 5.1 |
| F11 | 0.4 | 2.2 | 235 | 40.4 | 4.7 |
| F12 | 0.4 | 1.5 | 166 | 60 | 4.9 |
A: Surfactant concentration; B: oil concentration; Y1 particle size; Y2: In vitro release study; Y3: Hemolysis.