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Study procedures. C57BL/6 mice were treated on the dorsal skin and right ear pinna for 4 days with five different treatment regimens as described in the Section 4. C57BL/6 mice were treated daily with vehicle control, IMQ, IMQ + TCDD, IMQ + Rapa, or IMQ + TCDD + Rapa applied on their shaved back skin and right ears. IMQ: imiquimod, Rapa: rapamycin.
