Figure 7.

The effects of TCDD, rapamycin, or cotreatment of both on proinflammatory cytokine mRNA expression changes in the skin tissues of a psoriasis mouse model. (A–E) qPCR analysis of TNF-α, IL-6, IL-17A, IL-22, and IL-23 was performed in skin tissue from 5 different study groups (n = 5 per group). Data represent mean ± SD of three independent experiments (each performed in duplicate). Statistical differences were determined by one-way analysis of variance (ANOVA) with Dunnett’s test. * p < 0.05; ** p < 0.01; *** p < 0.001. Rapa: rapamycin; IMQ: imiquimod.