Table 1.
Clinical characteristics and metabolic risk profile in subjects grouped in quartiles of MEEi (mL/s/g).
| MEEi ≤ 0.41 (n = 111) | MEEi 0.42–0.54 (n = 120) | MEEi 0.54–0.67 (n = 125) | MEEi ≥ 0.67 (n = 124) | p for Trend | |
|---|---|---|---|---|---|
| Age (years) | 48 ± 9 | 49 ± 9 | 46 ± 9 | 47 ± 9 | 0.021 |
| Women | 42% | 58% | 68% | 75% | <0.001 |
| BMI (kg/m2) | 33 ± 5 | 32 ± 4 | 32 ± 4 | 31 ± 4 | <0.001 |
| Fat Free mass (%) | 65 ± 13 | 60 ± 13 | 58 ± 11 | 56 ± 10 | <0.001 |
| Hypertension | 85% | 76% | 71% | 65% | <0.001 |
| Obesity | 75% | 62% | 67% | 48% | <0.001 |
| Diabetes | 10% | 9% | 4% | 7.5% | 0.146 |
| Systolic BP (mmHg) | 135 ± 16 | 132 ± 17 | 126 ± 14 | 125 ± 15 | <0.001 |
| Diastolic BP (mmHg) | 86 ± 9 | 84 ± 10 | 80 ± 8 | 79 ± 8 | <0.001 |
| Heart rate (bpm) | 72 ± 11 | 70 ± 10 | 67 ± 10 | 63 ± 9 | <0.001 |
| Fasting plasma glucose (mmol/L) | 5.05 ± 0.5 | 5 ± 0.4 | 5 ± 0.5 | 4.8 ± 0.4 | 0.005 |
| eGFR (ml/min/1.73m2) | 94.7 ± 14 | 95.5 ± 13 | 98.6 ± 13 | 96.1 ± 13 | 0.106 |
| Total cholesterol (mmol/L) | 5.5 ± 1.2 | 5.5 ± 1 | 5.3 ± 1.1 | 5.5 ± 0.9 | 0.243 |
| HDL-cholesterol (mmol/L) | 1.2 ± 0.3 | 1.3 ± 0.4 | 1.3 ± 0.3 | 1.4 ± 0.3 | 0.013 |
| Triglycerides (mmol/L) | 1.8 ± 1.5 | 1.5 ± 0.8 | 1.4 ± 0.9 | 1.3 ± 0.6 | <0.001 |
| HOMA-IR | 4.3 ± 6.5 | 3.8 ± 4.9 | 3.4 ± 4.7 | 2.8 ± 2.1 | 0.019 |