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. 2021 Apr 12;22(8):3974. doi: 10.3390/ijms22083974
UVR Ultraviolet radiation
ROS Reactive oxygen species
NADPH Nicotinamide adenine dinucleotide phosphate
HaCaT Human epidermal keratinocytes
IL Interleukin
TNF- α Tumor necrosis factor α
NF-kB Nuclear factor kappa light chain enhancer of activated B
HIF-1a Hypoxia-inducible factor 1-alpha
Nrf-2 Nuclear factor erythroid 2-related factor 2
AP-1 Activator protein 1
SC Stratum corneum
TEWL Transepidermal water loss
EGFR Epidermal growth factor receptor
TGFR Transforming growth factor receptors
TLRs Toll-like receptors
TNFR TNF-α receptor
CSF Colony stimulating factors
TGF-α Transforming growth factor α
TGF- β Transforming growth factor β
HMGB1 High-mobility group box 1
PDGF Platelet-derived growth factor
COX2 Cyclooxygenases 2
MAP Mitogen-activated protein
PGE2 Prostaglandin 2
TβRII TGF-β type II receptor
ECM Extracellular matrix
HDFs Human dermal fibroblasts
NHDFs Normal human dermal fibroblasts
HSF2 Human skin fibroblasts
MED Minimal erythemal dose
iNOS Inducible nitric oxide synthase
FGF Fibroblast growth factors
MMPs Matrix-degrading metalloproteinases
MMP-1 Collagenase-1
MMP-3 Stromelysin-1
MMP-9 Gelatinase B
COL1A2 Type I collagen gene
SASP Senescence-associated secretory phenotype