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. 2021 Apr 12;10(4):838. doi: 10.3390/foods10040838

Table 1.

Capital expenditure (CAPEX), annual operating costs (AOC), and cost of goods sold (COGS) for transgenic thaumatin production facilities. Depreciation is based on the 10-year straight line method.

Facility Upstream
(Field)
Upstream
(Indoor)
Downstream
(With Chromatography)
CAPEX ($ million) 10.2 186 115
AOC without depreciation ($ million) 3.59 96.1 25.0
COGS without depreciation ($/kg) 71.7 1920 499
AOC with depreciation
($ million)
4.22 110 35.3
COGS with depreciation ($/kg) 84.5 2200 706
Upstream
(Field)
Upstream
(Indoor)
Downstream
(Without Chromatography)
CAPEX ($ million) 9.22 157 83.7
AOC without depreciation ($ million) 3.00 80.3 12.8
COGS without depreciation ($/kg) 60.0 1600 258
AOC with depreciation
($ million)
3.56 94.3 20.4
COGS with depreciation ($/kg) 71.2 1890 408