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. 2021 Apr 13;22(8):4020. doi: 10.3390/ijms22084020

Table 1.

International Clinical Disease Severity Scale for diabetic retinopathy (DR).

Disease Ophthalmoscopy Findings
No apparent DR No ocular findings
NPDR No NV
Mild Microaneurysms only
Moderate Microaneurysms + blot haemorrhages, hard exudates, cotton wool spots (but less than in severe NPDR)
Severe Intraretinal haemorrhages (≥20 in each quadrant)
Definite venous beading (in two quadrants)
Intraretinal microvascular abnormalities (IRMA) (in one quadrant)
No signs of proliferative retinopathy
PDR Neovascularisation or vitreous/preretinal haemorrhage/tractional retinal detachment
DME = retinal thickening of hard exudates in the posterior pole
Mild Some retinal thickening or hard exudates in the posterior pole but distant from the centre of the macula
Moderate Retinal thickening or hard exudates approaching the centre of the macula but not involving the fovea
Severe Retinal thickening or hard exudates involving the centre of the macula

DR = diabetic retinopathy; NPDR = nonproliferative diabetic retinopathy; NV = neovascularisation; PDR = proliferative diabetic retinopathy; DME = diabetic macular oedema.