Table 2.

Drugs predicted by the L1000FDW software.

Sig_ID	Drug	Drug Category	Indication	Similarity Score	p-Value	q-Value	Z-Score	Combined Score
CPC007_A375_24H:BRD-K03067624-003-19-3:10	emetine	emetine alkaloids	anti-protozoal	−0.1948	1.40 × 10−11	2.85 × 10−8	1.78	−19.35
CPC017_A375_6H:BRD-K76674262-001-01-7:10	homoharringtonine	cephalotaxus alkaloids	CML	−0.1818	1.32 × 10−10	1.49 × 10−7	1.71	−16.86
CPC004_VCAP_24H:BRD-A01643550-001-03-1:10	prednisolone	synthetic glucocorticoid	anti-inflammatory or immunosuppressive agent	−0.1688	2.09 × 10−9	1.01 × 10−6	1.81	−15.74
CPC002_VCAP_24H:BRD-K90553655-001-03-6:10	testosterone	anabolic steroid	hypogonadism	−0.1688	2.42 × 10−9	1.12 × 10−6	1.83	−15.77
CPC017_HT29_6H:BRD-K07691486-001-04-9:10	roscovitine	synthetic organic	kinase inhibitor	−0.1558	1.58 × 10−8	4.10 × 10−6	1.67	−13.04
CPD002_PC3_24H:BRD-K08547377-394-01-9:10	irinotecan	DNA replication inhibitor	colon cancer	−0.1429	1.39 × 10−7	2.06 × 10−5	1.66	−11.38
CPC006_PC3_6H:BRD-K82135108-001-01-9:10	elesclomol	sulfur compounds	anti-cancer activity	−0.1429	1.36 × 10−7	2.06 × 10−5	1.77	−12.16
PCLB002_A375_24H:BRD-K02130563:1.11	panobinostat	non-selective histone deacetylase (HDAC) inhibitor	multiple myeloma and other cancers	−0.1429	2.04 × 10−7	2.55 × 10−5	1.59	−10.64
MUC.CP006_MCF7_6H:BRD-K77987382-001-08-2:10	mebendazole	benzimidazole	antihelmintic	−0.1429	1.22 × 10−7	1.97 × 10−5	1.63	−11.26
CPC005_PC3_24H:BRD-A07000685-001-03-6:10	hydrocortisone	adrenal glucocorticoid	immune and allergic disorders, adrenal insufficiency disorders	−0.1429	1.92 × 10−7	2.45 × 10−5	1.78	−11.93