Table 1.
Percentage of PS amplitude values of BST recorded in the CA1 region of hippocampal slices from the control group and groups treated with different concentrations of NAA at different times.
| TIME (min) | CTRL (PS% Amplitude) |
NAA 0.005 mIU/mL (PS% Amplitude) |
NAA 0.05 mIU/mL (PS% Amplitude) |
NAA 0.5 mIU/mL (PS% Amplitude) |
NAA 10 mIU/mL (PS% Amplitude) |
SIGNIFICANCE between Groups at Different Times |
|---|---|---|---|---|---|---|
| 5 | 99.4 ± 14.1 | 103.3 ± 11.0 | 112.8 ± 24.0 | 103.6 ± 18.4 | 109.8 ± 27.5 | no significance |
| 35 | 101.5 ± 16.9 | 94.0 ± 3.4 | 125.7 ± 28.1 | 146.1 ± 27.2 | 179.4 ± 52.1 | CTRL vs. NAA 10 mIU/mL, *** p < 0.001 |
| 65 | 95.6 ± 17.5 | 100.5 ± 12.4 | 124.2 ± 22.8 | 171.9 ± 35.9 | 233.5 ± 62.6 | CTRL vs. NAA 0.5 mIU/mL, *** p < 0.001; CTRL vs. NAA 10 mIU/mL, **** p < 0.0001 |
PS: Population Spikes; BST: Basal Synaptic Transmission; NAA: Neuraminidase; CTRL: control group; ***: p < 0.001; ****: p < 0.0001.