Table 1.
Demographic and clinical variables as predictors of non-adherence at bivariate level
| Variables | Adherent | COR (95% CI) | p value | |
|---|---|---|---|---|
| Yes | No | |||
| n (%) | n (%) | |||
| Gender | ||||
| Male | 89 (57.1) | 49 (57.0) | 1.00 (0.59, 1.70) | 0.991 |
| Female | 67 (42.9) | 37 (43.0) | Ref | |
| Educational level | ||||
| Middle | 30 (19.2) | 24 (27.9) | 3.00 (1.16, 7.73) | 0.023a |
| Secondary | 68 (43.6) | 45 (52.3) | 2.48 (1.04, 5.90) | 0.040a |
| Higher | 28 (17.9) | 9 (10.5) | 1.25 (0.41, 3.56) | 0.735 |
| Primary/no formal education | 30 (19.2) | 8 (9.3) | Ref | |
| Employment | ||||
| Unemployed | 114 (73.1) | 55 (64) | 0.65 (0.37, 1.15) | 0.140 |
| Employed | 42 (26.9) | 31 (36) | Ref | |
| Marital status | ||||
| Single | 67 (42.9) | 43 (50) | 2.09 (0.85, 5.03) | 0.102 |
| Married | 63 (404) | 35 (40.7) | 1.01 (0.74, 4.14) | 0.195 |
| Divorced/widowed/separated | 26 (16.7) | 8 (9.3) | Ref | |
| Residence | ||||
| Asmara | 100 (64.1) | 62 (72.1) | 1.45 (0.81, 2.57) | 0.207 |
| Out of Asmara | 56 (35.9) | 24 (27.9) | Ref | |
| Smoking | ||||
| Yes | 24 (15.4) | 24 (27.9) | 2.13 (1.12, 4.04) | 0.021a |
| No | 132 (84.6) | 62 (72.1) | Ref | |
| Alcohol | ||||
| Yes | 12 (7.7) | 13 (15.1) | 2.14 (0.93, 4.92) | 0.074 |
| No | 144 (92.3) | 73 (84.9) | Ref | |
| Number of APs | ||||
| Single | 84 (53.8) | 39 (45.3) | 0.71 (0.42, 1.21) | 0.206 |
| Multiple | 72 (46.2) | 47 (54.7) | Ref | |
| ADRs-Counseling | ||||
| Yes | 81 (51.9) | 41 (47.7) | 0.84 (0.50, 1.43) | 0.527 |
| No | 75 (48.1) | 45 (52.3) | Ref | |
| Drug formulation | ||||
| Long acting injectable | 38 (24.4) | 13 (15.1) | 0.93 (0.51, 1.68) | 0.806 |
| Oral and long acting injectable | 69 (44.2) | 44 (51.2) | 0.54 (0.26,1.12) | 0.097 |
| Oral | 49 (31.4) | 29 (33.7) | Ref | |
| Variables | Adherent | COR (95% CI) | p value | |
|---|---|---|---|---|
| Yes | No | |||
| Md (IQR) | Md (IQR) | |||
| Age | 39.0 (16.0) | 19.0 (15.0) | 0.990 (0.9668,1.0139) | 0.412 |
| Weight | 60.0 (18.0) | 60.0 (12.0) | 0.004 (0.9809, 1.0267) | 0.758 |
| Duration of illness | 135.5 (144.0) | 159.0 (163.3) | 1.000 (0.9981, 1.0027) | 0.734 |
| Mean antipsychotic dose | 196.2 (196.2) | 237.5 (226.4) | 1.002 (1.0001, 1.0037) | 0.034a |
| Red herrings score | 0.0 (2.0) | 0.0 (4.0) | 1.098 (1.0073, 1.1975) | 0.033a |
COR Crude odds ratio, CI confidence interval, Md median, IQR inter quartile range, n number of participants
aSignificant