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. 2021 Apr 12;22(8):3970. doi: 10.3390/ijms22083970
ER Endoplasmic reticulum
PMEL17 Melanocytes lineage-specific antigen gp100
MART-1 Melanoma antigen recognized by T cell-1
GPNMB Glycoprotein nonmetastatic melanoma protein b
TYR Tyrosinase
TYRP1 Tyrosinase-related protein-1
TYRP2 Tyrosinase-related protein-2
BLOCs Biogenesis of lysosome-related organelles complexes
AP-1 Activator protein 1
MLPH Melanophilin
MYO5A Myosin-Va
RAB27A Ras-related protein Rab27A
MITF Microphthalmia-associated transcription factor
DAMPs Damage-associated molecular patterns
PAMPs Pathogen-associated molecular patterns
PRRs Pattern-recognition receptors
TLRs Toll-like receptors;
NLRs NOD-like receptors
RLRs Retinoic acid-inducible gene-I-like receptors
MyD88 Myeloid differentiation primary response protein-88
TAM Tyro3, Axl, and Mer receptors
NF-κβ Nuclear factor kappa-B
IRF Interferon regulatory factor
IL Interleukin
TNF Tumor necrosis factor
IKK IκB kinase
JAK-STAT Janus kinase-signal transducer and activator of transcription
MAPKs Mitogen-activated protein kinases
MKK MAPK kinase
MKKK MAPK kinase kinase
Erk1/2 Etxracellular signal-regulated kinase ½
JNK c-Jun N-terminal kinases
UVR Ultraviolet radiation
TNFR Tumor necrosis factor receptor
EGFR Epidermal growth factor receptor
PGE2 Prostaglandin E2
PGF2α Prostaglandin F2α
GM-CSF Granulocyte-macrophage colony stimulating factor
IFN-γ Interferon-γ
PKA Protein kinase A
NK cell Natural killer cell
NKT cell Natural killer T cell
Th T helper cell
cAMP Cyclic adenosine monophosphate
PAX3 Paired box protein Pax-3
SOX10 Sex-determining region Y-box 10
KIT Stem cell growth factor receptor (CD117)
SCF Stem cell growth factor
EDN Endothelin
NGF Nerve growth factor
HGF Hepatocyte growth factor
α-MSH α-Melanocyte-stimulating hormone
ACTH Adrenocorticotropic hormone
MLPH melanophilin
CREB cAMP responsive-element binding protein
SIK Salt-inducible kinase
CRTC CREB-regulated transcription coactivator
MITF-M Melanocytes-specific MITF isoform