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. 2021 Apr 9;10(4):862. doi: 10.3390/cells10040862

Figure 1.

Figure 1

Influence of hypoxia on melanoma progression. Detailed descriptions can be found in the text. Abbreviations: miR, microRNA; MHC I, major histocompatibility complex class I; HMGB1, high mobility group box 1 protein; IL-8, interleukin 8; VEGF, vascular endothelial growth factor; RLIP76, Ral-interacting protein of 76 kDa; Bcl-2, B-cell CLL/lymphoma 2; BNIP3, Bcl-2 interacting protein 3; HIF-1α, hypoxia-inducible factor 1 α; Mcl-1, myeloid cell leukemia 1; BAD, Bcl-2-associated agonist of cell death; AKAP12v2, A-kinase anchor protein 12 variant 2; MMP2, matrix metalloproteinase 2; LRIG1, leucine-rich repeats and Ig-like domains 1; MITF, microphthalmia-associated transcription factor; GM-3, monosialodihexosylganglioside.