Table 4.
Period | A: Donepezil 5 mg Mean ± Std Dev Median IQR |
B: Donepezil 10 mg Mean ± Std Dev Median IQR |
C: Donepezil + DSS Mean ± Std Dev Median IQR |
Significance p Value |
---|---|---|---|---|
Basal | 2632 ± 1855 | 1938 ± 1658 | 5812 ± 13433 | A-B: NS |
2153 | 1441 | 1438 | A-C: NS | |
1226–3616 | 825–2550 | 668–4139 | B-C: NS | |
T1 | 7459 ± 14605 | 3068 ± 3963 | 4330 ± 5648 | A-B: p = 0.001 |
2772 | 1957 | 2262 | A-C: NS | |
1555–5703 | 592–3426 | 1392–5031 | B-C: NS | |
T3 | 4337 ± 11106 | 4891 ± 12753 | 3254 ± 2955 | A-B: NS |
570 | 579 | 2205 | A-C: p < 0.001 | |
296–1748 | 200–1555 | 1370–3932 | B-C: p < 0.001 | |
T8 | 769 ± 1347 | 1015 ± 820 | 1227 ± 1780 | A-B: p < 0.001 |
408 | 803 | 745 | A-C: p < 0.001 | |
205–712 | 414–1414 | 461–1064 | B-C: NS | |
T10 | 2123 ± 7376 | 838 ± 1007 | 2234 ± 2457 | A-B: NS |
342 | 587 | 739 | A-C: p < 0.001 | |
209–817 | 168–1180 | 304–4497 | B-C: p < 0.001 | |
T12 | 762 ± 1623 | 5176 ± 11805 | 3569 ± 4773 | A-B: p = 0.002 |
346 | 703 | 1114 | A-C: p < 0.001 | |
191–637 | 193–3181 | 378–5583 | B-C: NS | |
T16 | 1475 ± 4554 | 652 ± 834 | 2068 ± 2235 | A-B: NS |
319 | 269 | 1201 | A-C: p < 0.001 | |
184–603 | 113–946 | 473–2740 | B-C: p < 0.001 | |
T20 | 3023 ± 9753 | 779 ± 1630 | 531 ± 393 | A-B: p < 0.001 |
423 | 215 | 425 | A-C: NS | |
208–1129 | 77–987 | 184–925 | B-C: p = 0.007 | |
T22 | 527 ± 426 | 3061 ± 11286 | 900 ± 1074 | A-B: NS |
422 | 253 | 559 | A-C: NS | |
202–681 | 124–993 | 239–1264 | B-C: NS |
DSS: dextran sodium sulfate; IQR: interquartile range; NS: not significant; Std Dev: standard deviation.