Table 2.
Monocyte chemoattractant protein-1 and high-sensitivity C-reactive protein levels, and preoperative variables related to the mental condition of participants assessed in a univariate analysis.
| Variable | Non-Delirious a (n = 116) |
Delirious a (n = 61) |
Effect Size b | p |
|---|---|---|---|---|
| Depression | 9 (7.8%) | 24 (39.0%) | 0.385 | <0.001 * |
| Anxiety disorders | 5 (4.3%) | 9 (14.7%) | 0.184 | 0.02 * |
| Alcohol addiction c | 8 (6.9%) | 5 (8.2%) | 0.024 | 0.768 |
| MMSE score | 28 (26–29) | 28 (26–29) | 0.130 | 0.149 |
| CDT score | 7 (5–7) | 6 (5–7) | 0.066 | 0.458 |
| Preoperative MCP-1 (ng/mL) | 353.4 (290.7–446.0) 400.3 (114.6–1416.4) d |
458.4 (374.1–554.7) 483.5 (174.33–987.6) d |
−0.404 | <0.001 * |
| Postoperative MCP-1 (ng/mL) | 486.9 (359.8–712.1) 671.2 (202.0–2069.3) d |
598.9 (386.1–765.5) 712.5 (154.0–10688.1) d |
−0.129 | 0.16 |
| Preoperative hsCRP (mcg/mL) | 2.97 (0.94–7.57) 9.92 (0.04–151.5) d |
7.6 (2.2–12.0) 10.7 (0.08–102.7) d |
−0.302 | 0.001 * |
| Postoperative hsCRP (mcg/mL) | 151.6 (93.9–207.2) 177.3 (9.5–2116.1) d |
212.88 (124.6–277.6) 266 (30.4–4009.6) d |
−0.322 | <0.001 * |
CDT: Clock Drawing Test; hsCRP: High-sensitivity C-reactive protein; MMSE: Mini-Mental State Examination; MCP-1: Monocyte chemoattractant protein-1. a For continuous variables, the medians and interquartile ranges (IQRs) are given; for categorical variables, the number of observations (n) and fraction (%) were calculated; b for continuous variables rank-biserial correlation coefficient was calculated; for categorical variables, Cramer’s V coefficient was presented; c only patients with at least 3 months abstinence were included; d for more detailed presentation of the data, the means and ranges were also given; * indicates significance (p < 0.1).