Table 5.
Characteristics of peptide-decorated and native NPs.
| Code | Composition (wt%) | Dh a (nm) | PDI a | ζ b (mV) | E.E. c (%) |
|---|---|---|---|---|---|
| NPs 1 | GBVA10-9PMLABe73/PMLABe73 (10/90) | 108 ± 60 | 0.18 | −48 ± 7 | 76 |
| NPs 2 | GBVA10-9PEG62-b-PMLABe73/PMLABe73 (10/90) | 66 ± 30 | 0.21 | −46 ± 8 | 68 |
| NPs 3 | GBVA10-9PEG62-b-PMLABe73/PEG42-b-PMLABe73 (10/90) | 71 ± 50 | 0.28 | −37 ± 5 | 80 |
| NPs 4 | CPBPMLABe73/PMLABe73 (10/90) | 139 ± 60 | 0.12 | −54 ± 10 | 55 |
| NPs 5 | CPBPEG62-b-PMLABe73/PMLABe73 (10/90) | 128 ± 60 | 0.13 | −50 ± 6 | 93 |
| NPs 6 | CPBPEG62-b-PMLABe73/PEG42-b-PMLABe73 (10/90) | 102 ± 60 | 0.30 | −43 ± 6 | 81 |
| NPs 7 | GBVA10-9scrPMLABe73/PMLABe73 (10/90) | 115 ± 50 | 0.16 | −58 ± 8 | 66 |
| NPs 8 | GBVA10-9scrPEG62-b-PMLABe73/PMLABe73 (10/90) | 106 ± 60 | 0.17 | −56 ± 7 | 95 |
| NPs 9 | GBVA10-9scrPEG62-b-PMLABe73/PEG42-b-PMLABe73 (10/90) | 70 ± 50 | 0.28 | −51 ± 8 | 71 |
| NPs 10 | CPBscrPMLABe73/PMLABe73 (10/90) | 163 ± 60 | 0.10 | −53 ± 8 | 76 |
| NPs 11 | CPBscrPEG62-b-PMLABe73/PMLABe73 (10/90) | 146 ± 70 | 0.13 | −52 ± 6 | 95 |
| NPs 12 | CPBscrPEG62-b-PMLABe73/PEG42-b-PMLABe73 (10/90) | 74 ± 50 | 0.23 | −47 ± 10 | 77 |
| NPs 13 | PMLABe73 | 71 ± 40 | 0.21 | −62 ± 8 | 74 |
| NPs 14 | PEG42-b-PMLABe73/PMLABe73 (10/90) | 62 ± 40 | 0.22 | −59 ± 9 | 49 |
| NPs 15 | PEG42-b-PMLABe73 | 64 ± 50 | 0.27 | −55 ± 7 | 68 |
a. Measured by DLS; b. Zeta pontential measured by DLS; c DiD Oil Encapsulation Efficiency measured by UV at 660 nm.