Table 1.
Summarized donor data for liver tissue samples used for immunohistochemical staining. Donor data are summarized based on the underlying disease. In addition, age; sex as well as histopathological findings for steatosis, fibrosis and inflammation of the donors are indicated. For details on clinical data, see Table S1 in the Supplementary Materials.
| Summary | Donor ID | Age, Sex | Disease | Steatosis | Portal Fibrosis | Portal Inflammation |
|---|---|---|---|---|---|---|
|
Primary liver tumors (N = 7) |
D05 | 77, f 1 | HCC 2, low cholestasis |
5% | moderate | mild |
| D09 | 59, m 3 | HCC, cirrhosis |
5% | slight to moderate | mild to moderate | |
| D10 | 79, f | HCC, Child A cirrhosis |
60%, NAFLD 4/AFLD 5 |
cirrhosis | moderate | |
| D04 | 46, f | iCCA 6, low cholestasis |
15% | moderate | moderate, mild florid | |
| D06 | 77, f | pCCA 7, moderate cholestasis |
5% | partly distinct, also portoportal | mild, also periportal | |
| D07 | 65, f | pCCA, moderate cholangitis and cholestasis |
5% | slight | mild | |
| D08 | 75, m | pCCA, moderate cholestasis |
5% | moderate | mild to moderate, also periportal | |
|
Secondary liver tumors (N = 3) |
D02 | 74, f | CRLM 8 + CTx 9 | 5% | - | mild |
| D03 | 50, m | CRLM + CTx | NAFLD/AFLD | slight | mild | |
|
D01 (control) |
38, f | CRLM | - | low | mild to moderate | |
|
Benign liver tumors (N = 5) |
D11 (control) |
69, m | Bilioma (infected) | - | highly chronic, partly granulating | moderate florid |
|
D12 (control) |
24, f | Adenoma | - | slight | mild | |
|
D13 (control) |
41, m | FNH 10 | 5% | slight | mild | |
|
D14 (control) |
26, f | Adenoma | 75% | slight to moderate | mild | |
|
D15 (control) |
55, f | Hemangioma | 5% | slight | mild |
1 f: female, 2 HCC: hepatocellular carcinoma, 3 m: male, 4 NAFLD: non-alcoholic fatty liver disease, 5 AFLD: alcoholic fatty liver disease, 6 iCCA: intrahepatic cholangiocarcinoma, 7 pCCA: perihilar cholangiocarcinoma, 8 CRLM: colorectal liver metastasis, 9 CTx: chemotherapy, 10 FNH: focal nodular hyperplasia.