Table 3.
Mean and standard errors (SE) of headache features in the three months before first pandemic phase (T0), during first-phase lockdown (T1), during second wave (T2). Headache frequency and number of symptomatic drugs are normalized in a monthly index. Headache intensity is rated on a 0–10 numeric scale. Results of repeated measures ANOVA and repeated contrasts are reported. Degree of freedom 2, degree of error 302.
| Pandemic Phase | Mean | SE | 95% CI | ANOVA | Contrasts | |
|---|---|---|---|---|---|---|
| Lower | Upper | |||||
| Headache Frequency | ||||||
| T0 | 9.556 | 0.471 | 8.629 | 10.483 | F 11.86 | T0 vs. T1 p 0.03 |
| T1 | 8.447 | 0.474 | 7.515 | 9.380 | p < 0.0001 | T1 vs. T2 p < 0.0001 |
| T2 | 10.750 | 0.594 | 9.582 | 11.918 | T0 vs. T2 p 0.03 | |
| Acute Medication Use | ||||||
| T0 | 7.997 | 0.573 | 6.869 | 9.124 | F 8.17 | T0 vs. T1 p 0.03 |
| T1 | 6.957 | 0.588 | 5.801 | 8.113 | p < 0.0001 | T1 vs. T2 p < 0.0001 |
| T2 | 9.503 | 0.630 | 8.263 | 10.743 | T0 vs. T2 p 0.03 | |
| Headache Intensity | ||||||
| T0 | 6.896 | 0.119 | 6.661 | 7.131 | F 5.69 | T0 vs. T1 p < 0.001 |
| T1 | 6.546 | 0.125 | 6.300 | 6.793 | p 0.004 | T1 vs. T2 p n.s. |
| T2 | 6.762 | 0.115 | 6.535 | 6.989 | T0 vs. T2 p n.s. | |