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. 2021 Apr 10;13(4):531. doi: 10.3390/pharmaceutics13040531

Table 4.

Evaluation of NLC-Rho after release studies (72 h). Parameters evaluated were hydrodynamic size (nm), PdI and zeta potential (mV). n = 3 ± SD.

Methodology Hydrodynamic Size
(nm ± SD)
PdI Zeta Potential
(mV ± SD)
NLC-Rho t = 0 106.7 ± 1.6 0.1 ± 0.01 −9.3 ± 0.6
Dialysis bag 25 °C 118.5 ± 1.7 0.1 ± 0.01 −18.4 ± 1.6
37 °C 115.1 ± 2.8 0.3 ± 0.01 −19.1 ± 1.3
Franz’s Cells 25 °C 117.2 ± 1.4 0.1 ± 0.01 −19.0 ± 1.0
37 °C 114.3 ± 3.1 0.2 ± 0.01 −16.0 ± 0.5