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. 2021 Apr 14;11(4):572. doi: 10.3390/biom11040572

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Strategies for sensitizing GBM to TRAIL-induced apoptosis. NP–TRAIL-CTX, nanoparticle coated with chitosan-polyethylene glycol-polyethyleneimine copolymer and chlorotoxin; NP-hADSCs-TRAIL, nanoparticle-engineered human adipose-derived stem cells overexpressing TRAIL; AgNPs-TRAIL, silver nanoparticles-TRAIL; HDACIs, histone deacetylase inhibitor; BH3-mimetics, Bcl-2 homology 3 mimetics; KPNB1, karyopherin β1.