Table 2.

Adjusted ORs and 95% CIs for any fracture or fall-related fracture according to severe hypoglycemia in patients with type 1 diabetes

	Any fracture		Fall-related fracture
	Without severe hypoglycemia	With severe hypoglycemia	Without severe hypoglycemia	With severe hypoglycemia
Number of patients with fracture	22	42	17	31
Number of total patients	226	162	226	162
Percentage of patients with fracture (%)	9.7	25.9	7.5	19.1
ORs (95% CI)
Unadjusted	1.0 (ref.)	3.25 (1.87 to 5.78)	1.0 (ref.)	2.90 (1.57 to 5.57)
Age-adjusted and sex-adjusted	1.0 (ref.)	3.12 (1.78 to 5.62)	1.0 (ref.)	2.98 (1.59 to 5.79)
Multivariate adjusted	1.0 (ref.)	2.10 (1.11 to 4.06)	1.0 (ref.)	1.93 (0.94 to 4.04)
Multivariate adjusted+neuropathy, diabetic retinopathy, DKD	1.0 (ref.)	2.11 (1.11 to 4.09)	1.0 (ref.)	1.91 (0.93 to 4.02)

Multivariate adjustments include age, sex, BMI, diabetes duration, current smoking habit, current drinking habit, exercise habit, family history of hip fracture, weight loss, and hemoglobin A_1c.

BMI, body mass index; DKD, diabetic kidney disease.