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. 2021 Apr 14;11(4):241. doi: 10.3390/metabo11040241

Table 1.

Annotated pepper compounds nominally associated with color.

Compound Name p-Value * FDR Green vs. Red ^ Green vs. Yellow ^ Red vs. Yellow ^ Class
Beta-Cryptoxanthin 0.000074 0.0080 0.010 0.677 0.035 Carotenoid
PC(O-20:0/O-1:0) 0.000128 0.0080 0.012 0.459 0.059 Phospholipid/PC
PC(O-20:0/O-1:0) 0.000129 0.0080 0.012 0.454 0.059 Phospholipid/PC
PI(18:2/13:0) 0.000154 0.0080 0.021 0.035 0.384 Phospholipid/PI
DG(22:6/18:0) 0.000769 0.0186 0.705 0.047 0.060 Glycerolipid/DG
PG(22:2/20:0) 0.001613 0.0318 0.052 0.117 0.999 Phospholipid/PG
DG(20:5/14:0) 0.002207 0.0366 0.053 0.071 0.761 Glycerolipid/DG
TG(22:2/15:0/20:5) 0.003347 0.0458 0.001 0.077 0.390 Glycerolipid/TG
PI(P-20:0/14:1) 0.003822 0.0458 0.014 0.002 0.331 Phospholipid/PI
MGDG(18:1/18:1) 0.003996 0.0458 0.999 0.095 NA Glycerolipid/MG
TG(18:4/20:5/18:4) 0.004664 0.0458 0.018 0.002 0.240 Glycerolipid/TG
Sucrose Acetate Isobutyrate (SAIB) 0.006477 0.0560 0.008 0.387 0.276 O-glycosyl
PI(22:1/16:0) 0.008388 0.0611 0.017 0.030 0.957 Phospholipid/PI
TG(22:4/20:2n6/22:5) 0.008509 0.0611 0.097 0.303 0.796 Glycerolipid/TG
PG(22:2/20:0) 0.008535 0.0611 0.132 0.144 0.767 Phospholipid/PG
DG(16:1/16:1) 0.009819 0.0631 0.101 0.491 NA Glycerolipid/DG
DG(22:2/14:1) 0.013877 0.0795 0.014 0.399 0.369 Glycerolipid/DG
2-ethenyl-2,4b,8,8-tetramethyl-tetradecahydrophenanthrene-3,5,10a-triol 0.015343 0.0817 0.100 0.464 0.566 Natural Product
Fargesin 0.018186 0.0895 0.276 0.534 0.155 Psoralen, from Fruits
Ascorbyl linoleate 0.021860 0.1026 0.160 0.358 0.940 Vitamin C metabolite
TG(22:4/15:0/22:4) 0.025945 0.1075 0.255 0.211 0.710 Glycerolipid/TG
TG(22:4/15:0/22:4) 0.028741 0.1146 0.248 0.250 0.824 Glycerolipid/TG
DG(18:4/15:0) 0.030030 0.1154 0.136 0.717 0.462 Glycerolipid/DG
PI(P-16:0/18:3) 0.031557 0.1198 0.131 0.044 0.587 Phospholipid/PI
Ascorbyl linoleate 0.032964 0.1222 0.514 0.164 0.309 Vitamin C metabolite
Ivermectin B1b 0.033354 0.1222 0.110 0.049 0.676 Antiparasitic drug
TG(20:4/15:0/22:5) 0.035029 0.1268 0.912 0.046 0.062 Glycerolipid/TG
Glycidyl oleate 0.037508 0.1293 0.174 0.436 0.891 Carboxylic ester
PE(15:0/20:0) 0.038016 0.1293 0.162 0.575 NA Phospholipid/PE
PC(14:0/20:5) 0.038145 0.1293 0.147 0.892 0.359 Phospholipid/PC
Ascorbyl linoleate 0.040104 0.1316 0.217 0.333 0.997 Vitamin C metabolite
PC(15:0/18:4) 0.041993 0.1364 0.245 0.294 0.926 Phospholipid/PC
MGDG(18:2/18:3) 0.043317 0.1392 0.398 0.220 0.553 Glycerolipid/MG
Goyaglycoside g 0.043762 0.1392 0.268 0.269 0.860 Cucurbitacin glycosides
Ramipril 0.045603 0.1408 0.991 0.253 NA Drug
PA(P-16:0/18:4) 0.047472 0.1438 0.518 0.211 0.436 Phospholipid/PA
all-trans-retinyl oleate 0.048268 0.1443 0.388 0.466 0.052 Prenol lipid
PC(14:1/20:5) 0.050091 0.1448 0.196 0.590 NA Phospholipid/PC
Archaetidylglycerol-myo-inositol 0.052834 0.1499 0.505 0.662 0.281 Lipid

Following database search, 39 compounds from the total 111 compounds found to be nominally associated with color (p < 0.05) (Table S2) were annotated. A total of 11 annotated compounds were found to differ by color with FDR adjusted p < 0.05 (above bold line). Compounds are sorted by p-value results following linear regression analysis (p-value *). Results (p-values ^) from pairwise comparisons of pepper color (green vs. red; green vs. yellow, red vs. yellow) are shown with p-values < 0.05 highlighted in gray.