Table 1.
Example CPPs and their bystander activities.
| CPPs | Classes | Sequences | Normalized AgNP Uptake |
|---|---|---|---|
| RPAR | Cationic | RPARPAR | 1.01 ± 0.01 |
| TAT | Cationic | YGRKKRRQRRR | 4.50 ± 0.23 |
| R9 | Cationic | RRRRRRRRR | 5.26 ± 0.48 |
| Transportan | Amphiphilic | GWTLNSAGYLLGKINLKALAALAKKIL | 12.01 ± 0.18 |
| MAP | Amphiphilic | KLALKLALKALKAALKLA | 0.92 ± 0.06 |
| PFV | Hydrophobic | PFVYLI | 0.95 ± 0.05 |
| Angiopep-2 | Hydrophobic | TFFYGGSRGKRNNFKTEEY | 0.91 ± 0.04 |
| HAI | Hydrophobic | HAIYPRH | 0.98 ± 0.03 |
Data presented here was mean ± s.d. of three independent experiments (n = 3). Median fluorescence intensity of CHO cells treated with the indicated peptide + bystander AgNPs was quantified by flow cytometry and normalized to that of cells with AgNPs alone. All the peptides used here were biotin-labeled ones. AgNP silver nanoparticle.