Figure 2.

Three-dimensional molecular structure of the mature CcLys2. (a) This graphic was generated with PyMOL 2.4 based on the CcLys2.pdb data. C₆–C₁₂₄, C₂₇–C₁₁₃, C₆₂–C₇₃, and C₆₉–C₈₇ indicate four disulfide bonds. The putative catalytic site (E32 and D50) is located between the α-helices and β-pleated sheets. (b) The highly conserved region (in fuchsin) is displayed in the structure. Homology model was performed by the ConSurf software (https://consurf.tau.ac.il/, 12 February 2021) and optimized using PyMOL 2.4.