Table 1.

Results of in vitro release model fitting for proteins and lipids from SBlyo. Kinetic elaborations were performed on release data obtained from at least three independent experiments for each batch. “~” indicates that the analysis performed was “ambiguous”; therefore, the fit does not nail down the values of all the parameters, and 95% confidence bounds cannot be reported. These latter data were not considered in the interpretation of results.

Model	Equation	Proteins/Lipids	Coefficients (95% Confidence Bounds)	Sum of Squares	R 2	Degrees of Freedom	SE
Higuchi	F(t) = k × t0.5	Proteins	k = 19.79	3,081,232	0.253	32	1.479
			(16.78, 22.80)
		Lipids	k = 1.498	43,540	−0.2396	32	0.1758
			(1.139, 1.856)
Higuchi (eq 2.12 from [32])	F(t) = 100 × (1 − C × exp (−k × t))	Proteins	C = −4.113	2,103,706	0.49	31	C
			(−5.216, −3.066)				0.5425
			k = −0.0002381				k
			(−0.0003286, −0.0001524)				0.00004424
		Lipids	C = 0.5763	28,621	0.1851	31	C
			(0.4179, 0.7419)				0.07758
			k = 0.0002817				k
			(0.0000523, 0.0007763)				0.0001296
Peppas–Sahlin	F(t) = k1 × tm + k2 × t(2 × m)	Proteins	k1 = ~				k1~
			k2 = ~				k 2 ~
			m = ~				m~
		Lipids	k 1 = ~				k 1 ~
			k 2 = ~				k 2 ~
			m = ~				m~
Ritger–Peppas	F(t) = k × tn	Proteins	k = 248.9	1,208,384	0.707	31	k
			(144.2, 394.5)				59.38
			n = 0.1725				n
			(0.1076, 0.2459)				0.03278
		Lipids	k = 33.89	21,454	0.3892	31	k
			(14.45, 63.50)				11.55
			n = 0.09547				n
			(0.001254, 0.2032)				0.04875
Zero-order	F(t) = k × t	Proteins	k = 0.3309	5,985,916	−0.4512	32	0.0378
			(0.2539, 0.4079)
		Lipids	k = 0.02411	66,142	−0.8831	32	0.003974
			(0.01602, 0.03221)
Korsmeyer–Peppas	F(t) = kKP × tn × Q0	Proteins	kKP = 248.9	1,208,384	0.707	31	kKP
			(144.2, 394.5)				59.38
			n = 0.1725				n
			(0.1076, 0.2459)				0.03278
		Lipids	kKP = 33.89	21,454	0.3892	31	kKP
			(15.45, 63.50)				11.55
			n = 0.09547				n
			(0.001254, 0.2032)				0.04875