2019-nCoV |
2019 novel coronavirus |
ACE2 |
angiotensin-converting enzyme 2 |
ACEI |
angiotensin-converting enzyme inhibitor |
AKT |
serine-threonine kinase |
Ambra1 |
activating molecule in Beclin 1-regulated autophagy |
AMPK |
protein kinase activated by AMP |
ARB |
angiotensin receptor blocker |
AT1 |
type 1 angiotensin II receptor |
AT2 |
type 2 angiotensin II receptor |
Atg/ATG |
autophagy-related protein/gene |
BCL-2 |
B-cell lymphoma 2 |
BCR-ABL |
breakpoint cluster region gene-Abelson proto-oncogene |
BECN1
|
beclin-1 gene |
CB1 |
cannabinoid receptor type 1 |
Beclin-1/Vps34 |
Beclin-1/vacuolar protein sorting 34 |
CCL |
chemokine (C-C motif) ligand |
COVID-19 |
Coronavirus Disease 2019 |
CoVs |
coronavirus |
CQ |
chloroquine |
DMVs |
double-membrane vesicles |
EBOV |
Ebola virus |
EIF4B |
eukaryotic translation initiation factor 4B |
EIF4F |
eukaryotic translation initiation factor 4F |
EIF4G1 |
Eukaryotic Translation Initiation Factor 4 Gamma 1 |
ER |
endoplasmic reticulum |
ERK |
extracellular signal-regulated kinase |
FDA |
Food and Drug Administration |
GABARAP |
gamma-aminobutyric acid receptor-associated protein |
GDI2 |
Guanosine nucleotide diphosphate dissociation inhibitor 2 |
GCs |
glucocorticoids |
GFP |
green fluorescent protein |
H1N1 |
influenza A |
HBV |
hepatitis B virus |
HCMV |
human cytomegalovirus |
HCQ |
hydroxychloroquine |
HCV |
hepatitis C virus |
HIV |
human immunodeficiency virus |
HNE |
human nasal epithelial cells |
HPV |
human papilloma virus |
HRV |
human rhinovirus |
HSV-1/HSV-2 |
human herpes simplex virus 1 and 2 |
IBV |
infectious Bronchitis Virus |
IECAs |
angiotensin-converting enzyme inhibitors |
IL-1β |
interleukin-1 β |
LASV |
Lassa virus |
LC3 |
microtubule-associated protein 1A/1B-light chain 3 |
LIR |
LC3-interacting region |
MAP1LC3 |
Microtubule-Associated Protein 1A/1B-Light Chain 3 |
MAPK |
mitogen-activated protein kinase |
MERS-CoV |
Middle-East respiratory syndrome coronavirus |
MHRA |
Medicines and Healthcare products Regulatory Agency |
mTORC1 |
mammalian target of rapamycin complex 1 |
NAADP |
Nicotinic Acid Adenine Dinucleotide Phosphate |
NF-κB |
nuclear factor kappa B |
NHS |
National Health Service |
NIH |
National Institute of Health |
Nsp |
nonstructural protein |
Orf |
open reading frame |
PEDV |
porcine epidemic diarrhea virus |
PI3K |
phosphoinositide 3-kinase |
PI3P |
phosphatidylinositol 3-phosphate |
PLP2-TM |
papain-like protease PLP2 |
PPARγ |
peroxisome proliferator-activated receptor γ |
RAS |
renin-angiotensin system |
RAB1A |
Ras-related protein Rab-1A |
RAB6A |
Ras-related protein Rab-6A |
RAB6D |
Ras-related protein Rab-6D |
RAB7A |
Ras-related protein Rab-7A |
RECOVERY |
Randomised Evaluation of COVID-19 Therapy |
RNA |
ribonucleic acid |
S |
Spike |
SARS-CoV |
severe acute respiratory syndrome coronavirus |
SARS-CoV-2 |
severe acute respiratory syndrome coronavirus 2 |
SCFD1 |
sec1 family domain containing 1 |
SQSTM1 |
sequestosome-1 |
SKP2 |
S-phase kinase-associated protein 2 |
SNAP29 |
synaptosome associated protein 29 |
SNARE |
N-ethylmaleimide-sensitive factor attachment protein receptor |
STAT3 |
signal transducer and activator of transcription 3 |
Stx17 |
Syntaxin 17 |
TFEB |
Transcription Factor EB |
TGEV |
transmissible gastroenteritis virus |
TMEV |
Theiler’s murine encephalomyelitis virus |
TMPRSS2 |
transmembrane serine protease 2 |
TNF-α |
tumor necrosis factor α |
TPCs |
Two-Pore Channels |
TRIM32 |
tripartite motif-containing 32 |
TRPML1 |
transient receptor potential mucolipin 1 |
ULK1 |
Unc-51-like autophagy activating kinase 1 |
UNC-5 |
Netrin receptor UNC-5 (Uncoordinated protein 5) |
USO1 |
General vesicular transport factor p115 |
USA |
United States of America |
VAMP8 |
lysosomal vesicle-associated membrane protein 8 |
VPS 34 |
vacuolar protein sorting 34 |
VPS 34-IN1 |
vacuolar protein sorting 34 inhibitor 1 |
WHO |
World Health Organization |
WIPI |
WD repeat domain phosphoinositide-interacting protein |
β-CoVs |
Betacoronavirus genus |