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. 2021 Apr 15;22(8):4067. doi: 10.3390/ijms22084067
2019-nCoV 2019 novel coronavirus
ACE2 angiotensin-converting enzyme 2
ACEI angiotensin-converting enzyme inhibitor
AKT serine-threonine kinase
Ambra1 activating molecule in Beclin 1-regulated autophagy
AMPK protein kinase activated by AMP
ARB angiotensin receptor blocker
AT1 type 1 angiotensin II receptor
AT2 type 2 angiotensin II receptor
Atg/ATG autophagy-related protein/gene
BCL-2 B-cell lymphoma 2
BCR-ABL breakpoint cluster region gene-Abelson proto-oncogene
BECN1 beclin-1 gene
CB1 cannabinoid receptor type 1
Beclin-1/Vps34 Beclin-1/vacuolar protein sorting 34
CCL chemokine (C-C motif) ligand
COVID-19 Coronavirus Disease 2019
CoVs coronavirus
CQ chloroquine
DMVs double-membrane vesicles
EBOV Ebola virus
EIF4B eukaryotic translation initiation factor 4B
EIF4F eukaryotic translation initiation factor 4F
EIF4G1 Eukaryotic Translation Initiation Factor 4 Gamma 1
ER endoplasmic reticulum
ERK extracellular signal-regulated kinase
FDA Food and Drug Administration
GABARAP gamma-aminobutyric acid receptor-associated protein
GDI2 Guanosine nucleotide diphosphate dissociation inhibitor 2
GCs glucocorticoids
GFP green fluorescent protein
H1N1 influenza A
HBV hepatitis B virus
HCMV human cytomegalovirus
HCQ hydroxychloroquine
HCV hepatitis C virus
HIV human immunodeficiency virus
HNE human nasal epithelial cells
HPV human papilloma virus
HRV human rhinovirus
HSV-1/HSV-2 human herpes simplex virus 1 and 2
IBV infectious Bronchitis Virus
IECAs angiotensin-converting enzyme inhibitors
IL-1β interleukin-1 β
LASV Lassa virus
LC3 microtubule-associated protein 1A/1B-light chain 3
LIR LC3-interacting region
MAP1LC3 Microtubule-Associated Protein 1A/1B-Light Chain 3
MAPK mitogen-activated protein kinase
MERS-CoV Middle-East respiratory syndrome coronavirus
MHRA Medicines and Healthcare products Regulatory Agency
mTORC1 mammalian target of rapamycin complex 1
NAADP Nicotinic Acid Adenine Dinucleotide Phosphate
NF-κB nuclear factor kappa B
NHS National Health Service
NIH National Institute of Health
Nsp nonstructural protein
Orf open reading frame
PEDV porcine epidemic diarrhea virus
PI3K phosphoinositide 3-kinase
PI3P phosphatidylinositol 3-phosphate
PLP2-TM papain-like protease PLP2
PPARγ peroxisome proliferator-activated receptor γ
RAS renin-angiotensin system
RAB1A Ras-related protein Rab-1A
RAB6A Ras-related protein Rab-6A
RAB6D Ras-related protein Rab-6D
RAB7A Ras-related protein Rab-7A
RECOVERY Randomised Evaluation of COVID-19 Therapy
RNA ribonucleic acid
S Spike
SARS-CoV severe acute respiratory syndrome coronavirus
SARS-CoV-2 severe acute respiratory syndrome coronavirus 2
SCFD1 sec1 family domain containing 1
SQSTM1 sequestosome-1
SKP2 S-phase kinase-associated protein 2
SNAP29 synaptosome associated protein 29
SNARE N-ethylmaleimide-sensitive factor attachment protein receptor
STAT3 signal transducer and activator of transcription 3
Stx17 Syntaxin 17
TFEB Transcription Factor EB
TGEV transmissible gastroenteritis virus
TMEV Theiler’s murine encephalomyelitis virus
TMPRSS2 transmembrane serine protease 2
TNF-α tumor necrosis factor α
TPCs Two-Pore Channels
TRIM32 tripartite motif-containing 32
TRPML1 transient receptor potential mucolipin 1
ULK1 Unc-51-like autophagy activating kinase 1
UNC-5 Netrin receptor UNC-5 (Uncoordinated protein 5)
USO1 General vesicular transport factor p115
USA United States of America
VAMP8 lysosomal vesicle-associated membrane protein 8
VPS 34 vacuolar protein sorting 34
VPS 34-IN1 vacuolar protein sorting 34 inhibitor 1
WHO World Health Organization
WIPI WD repeat domain phosphoinositide-interacting protein
β-CoVs Betacoronavirus genus