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. 2021 Apr 15;22(8):4070. doi: 10.3390/ijms22084070

Table 1.

Physiological parameters of wild-type (WT) and diabetic mice (db/db) at 10 and 12 months old. Blood glucose level is much higher in diabetic mice than in WT mice, as expected. Both body weight and kidney/body weight ratio are higher in diabetic mice than in WT mice. Albumin/Creatinine ratio is higher in diabetic mice compared with WT mice. Diabetic mice have more proteinuria compared with WT mice at both 10- and 12-months-old. A significant difference from WT mice is indicated by * p < 0.01.

WT
10 Months
Dbdb
10 Months
WT
12 Months
Dbdb
12 Months
Body weight (g) 30.64 ± 7.0 36.19 ± 6.5 30.11 ± 2.6 37.03 ± 6.9
Kidney/body weight (g/g) 0.926 ± 0.2 1.0 ± 0.2 * 0.96 ± 0.2 1.12 ± 0.2 *
Glucose levels (mg/dL) 119.4 ± 22.9 379.5 ± 65.5 * 90.8 ± 18.6 391.0 ± 90.9 *
Albumin/Creatinine ratio (μg/mg) 109.8 ± 20.6 530.6 ± 109 * 117.5 ± 19.7 650.4 ± 187 *
Proteinurea (mg/24h) 21.75 ± 8.0 35.44 ± 12.3 * 26.36 ± 6.7 42.58 ± 7.6 *