Table 2.
Dysregulated miRNAs associated with aromatase dysregulation in ovarian cancer.
| S. No. | Dysregulated miRNA/lncRNA | Chromosomal Location | Patient Samples | Cell Lines Used | Animal Model Used | References |
|---|---|---|---|---|---|---|
| Oncogenic | ||||||
| 1 | MIR224 | Xq28 | N.A. | KGN cell lines | Three-months-old nulliparous rats | [74,75] |
| Tumor Suppressive | ||||||
| 2 | MIR378 | 5q32 | N.A. | KGN cell lines | Porcine ovaries | [76,77] |
| 3 | MIR98 | Xp11.22 | Tissues from 52 ovarian cancer patients and 15 healthy control samples | Ishikawa cells | N.A. | [78,79] |
N.A., not available.