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. 2021 Apr 21;17:161–168. doi: 10.2147/VHRM.S300635

Table 3.

Multiple Logistic Regression Analyses of Risk Factors Associated with Framingham Risk Score for COVID‐19 Patients

Risk Factor Variables Framingham Risk Scoring
Low Risk (< 10%) (ref) Intermediate Risk (10–20%) High Risk (> 20%)
OR 95% CI P value OR 95% CI P value OR 95% CI P value
Age (yr) 1.35 1.19, 1.54 < 0.001* 1.62 1.38, 1.90 < 0.001*
Male sex (vs female) 0.06 0.01, 0.43 0.005* 0.01 0.00, 0.04 < 0.001*
Smoker (vs non-smoker) 5.52 0.29, 104.99 0.256 7.09 0.13, 396.99 0.340
Comorbidity present (vs not present)
Hypertension 5.65 1.08, 29.33 0.039* 10.98 1.75, 68.95 0.011*
Diabetes mellitus 23.02 2.43, 218.28 0.006* 210.57 18.26, 2428.16 < 0.001*
Ischemic Heart Disease 0.07 0.00, 6.17 0.246 0.16 0.00, 15.64 0.430
Chronic Kidney Disease 2.66 0.07, 99.90 0.596 0.42 0.00, 21.34 0.668
Chronic lung Disease 6.99 0.59, 83.57 0.124 14.69 0.70, 308.08 0.083
Heart Failure 2.76 0.07, 98.62 0.578 3.75 0.08, 159.57 0.489
Cerebrovascular accident 0.31 0.01, 7.19 0.471 1.55 0.07, 31.73 0.777
Outcomes
Pneumonia 21.19 1.41, 318.65 0.027* 13.63 0.81, 229.50 0.070
ARDS 2.17 0.21, 21.99 0.512 5.59 0.40, 78.60 0.202
Mechanical Ventilation 0.91 0.12, 7.01 0.663 0. 45 0.04, 5.18 0.523
Shock 0.12 0.00, 3.14 0.205 0.07 0.00, 2.09 0.124
Acute Kidney Injury 1.94 0.29, 12.75 0.491 3.16 0.35, 28.83 0.308
Heart Failure 12.09 0.20, 733.84 0.234 13.29 0.20, 886.21 0.227
ICU patients 0.65 0.09, 3.38 0.529 0.93 0.11, 7.89 0.951
LOS (day) 1.06 1.01, 1.12 0.028* 1.05 0.98, 1.11 0.169
Death 0.45 0.05, 3.97 0.476 0.47 0.04, 6.29 0.570

Note: *Statistically significant.

Abbreviations: ARDS, acute respiratory distress syndrome; ICU, intensive care unit; LOS, length of stay.