Table 3.
Risk Factor Variables | Framingham Risk Scoring | ||||||||
---|---|---|---|---|---|---|---|---|---|
Low Risk (< 10%) (ref) | Intermediate Risk (10–20%) | High Risk (> 20%) | |||||||
OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | |
Age (yr) | – | – | – | 1.35 | 1.19, 1.54 | < 0.001* | 1.62 | 1.38, 1.90 | < 0.001* |
Male sex (vs female) | – | – | – | 0.06 | 0.01, 0.43 | 0.005* | 0.01 | 0.00, 0.04 | < 0.001* |
Smoker (vs non-smoker) | – | – | – | 5.52 | 0.29, 104.99 | 0.256 | 7.09 | 0.13, 396.99 | 0.340 |
Comorbidity present (vs not present) | |||||||||
Hypertension | – | – | – | 5.65 | 1.08, 29.33 | 0.039* | 10.98 | 1.75, 68.95 | 0.011* |
Diabetes mellitus | – | – | – | 23.02 | 2.43, 218.28 | 0.006* | 210.57 | 18.26, 2428.16 | < 0.001* |
Ischemic Heart Disease | – | – | – | 0.07 | 0.00, 6.17 | 0.246 | 0.16 | 0.00, 15.64 | 0.430 |
Chronic Kidney Disease | – | – | – | 2.66 | 0.07, 99.90 | 0.596 | 0.42 | 0.00, 21.34 | 0.668 |
Chronic lung Disease | – | – | – | 6.99 | 0.59, 83.57 | 0.124 | 14.69 | 0.70, 308.08 | 0.083 |
Heart Failure | – | – | – | 2.76 | 0.07, 98.62 | 0.578 | 3.75 | 0.08, 159.57 | 0.489 |
Cerebrovascular accident | – | – | – | 0.31 | 0.01, 7.19 | 0.471 | 1.55 | 0.07, 31.73 | 0.777 |
Outcomes | |||||||||
Pneumonia | – | – | – | 21.19 | 1.41, 318.65 | 0.027* | 13.63 | 0.81, 229.50 | 0.070 |
ARDS | – | – | – | 2.17 | 0.21, 21.99 | 0.512 | 5.59 | 0.40, 78.60 | 0.202 |
Mechanical Ventilation | – | – | – | 0.91 | 0.12, 7.01 | 0.663 | 0. 45 | 0.04, 5.18 | 0.523 |
Shock | – | – | – | 0.12 | 0.00, 3.14 | 0.205 | 0.07 | 0.00, 2.09 | 0.124 |
Acute Kidney Injury | – | – | – | 1.94 | 0.29, 12.75 | 0.491 | 3.16 | 0.35, 28.83 | 0.308 |
Heart Failure | – | – | – | 12.09 | 0.20, 733.84 | 0.234 | 13.29 | 0.20, 886.21 | 0.227 |
ICU patients | – | – | – | 0.65 | 0.09, 3.38 | 0.529 | 0.93 | 0.11, 7.89 | 0.951 |
LOS (day) | 1.06 | 1.01, 1.12 | 0.028* | 1.05 | 0.98, 1.11 | 0.169 | |||
Death | 0.45 | 0.05, 3.97 | 0.476 | 0.47 | 0.04, 6.29 | 0.570 |
Note: *Statistically significant.
Abbreviations: ARDS, acute respiratory distress syndrome; ICU, intensive care unit; LOS, length of stay.