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Number of aberrant crypt foci (ACF) and number of polyps in the three experimental groups: high-fat diet (AOM-HF); HF supplemented with apple extract 1% (AOM-HF-AS1); and HF supplemented with apple extract 1.5% (AOM-HF-AS1.5). Data are Mean ± SEM. Different letters are significant at p < 0.05 by Mann-Whitney U-test.
