Table 1.

Degree of Quorum Sensing Inhibition (QSI) coumaperine derivatives *.

Entry	Monoconjugated-CP	Degree of QSI of CV026	Degree of QSI of KYC55
1.	CP-215	+++	+++
2.	CP-270	+++	+++
3.	CP-296	+++	+++
4.	CP-282	+++	++
5.	CP-289	+	+++
6.	CP-237	++	++
7.	CP-295	++	++
8.	CP-286	+	++
Entry	Diconjugated-CP	Degree of QSI of CV026	Degree of QSI of KYC55
9.	CP-154	+++	+++
10.	CP-158	+++	++
11.	CP-281 F1	++	+
12.	CP-38	++	+
13.	CP-9	++	+
Entry	Triconjugated-CP	Degree of QSI of CV026	Degree of QSI of KYC55
14.	CP-102	++	+

* Two tests were carried out using the reporter bacteria: Agrobacterium tumefaciens (KYC55) and Chromobacterium violaceum (CV026). Bacteria were grown overnight in soft agar with the appropriate autoinducer on a Thin Layer chromatography (TLC) plate where the different compounds were dried on 40 mM in ~20-µL acetonitrile, and their degree of QSI was measured semi-quantitatively by color intensity (+ low inhibition, ++ medium inhibition and +++ strong inhibition). Experiments were repeated three times, and the results were determined by considering at least 2 out of 3 experiments with the same results.