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In vivo anti-tumor effect of Ad-shRRM1 on RRM1 highly expressed RT112 xenografts. RT112 tumors, treated with Ad-shScramble or Ad-shRRM1, were enucleated 31 days after initiation of treatment. Images show (A) the appearance and (B) tumor volumes of RRM1 highly expressed RR112 xenografts in nude mice. (*: p < 0.05 versus Ad-shScramble treatment group).
