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. 2021 Apr 15;13(8):1907. doi: 10.3390/cancers13081907

Figure 2.

Figure 2

Quantification of minimal disseminated disease by digital PCR for NPM1-ALK fusion transcripts in patients with anaplastic large cell lymphoma. (a) Correlation of quantification of minimal disease in blood or bone marrow of patients with anaplastic large cell lymphoma measured by RQ-PCR or digital PCR for NPM1–ALK. (b) Five-year event-free survival (EFS) of 75 children with NPM-ALK-positive anaplastic large cell lymphoma according to minimal disseminated disease in bone marrow quantified by digital PCR using a cut-off of 30 copies NPM1-ALK/104 copies ABL. (from Damm-Welk et al., [50]).