Table 6.
Road Exposures | Unadjusted OR (95%CI) |
p-Value | Adjusted OR (95%CI) * |
p-Value | |
---|---|---|---|---|---|
Birth distance to major road, meter | <100 | 1.48 (0.98–2.22) | 0.06 | 1.26 (0.81–1.95) | 0.31 |
100–200 | 1.20 (0.75–1.93) | 0.44 | 0.95 (0.65–1.38) | 0.78 | |
201–300 | 1.77 (1.11–2.82) | 0.02 | 1.62 (0.92–2.85) | 0.10 | |
>300 | Ref | --- | Ref | --- | |
Birth distance to primary road, meter | <400 | 1.34 (0.54–3.30) | 0.53 | 1.13 (0.53–2.41) | 0.76 |
400–1000 | 1.11 (0.81–1.52) | 0.53 | 0.95 (0.64–1.39) | 0.78 | |
>1000 | Ref | --- | Ref | --- | |
Pooled distance to major road, meter † | <100 | 1.69 (1.09–2.61) | 0.02 | 1.51 (1.00–2.28) | 0.05 |
100–200 | 1.17 (0.81–1.69) | 0.40 | 0.85 (0.54–1.34) | 0.49 | |
201–300 | 1.62 (1.10–2.39) | 0.02 | 1.62 (1.16–2.25) | 0.005 | |
>300 | Ref | --- | Ref | --- | |
Pooled distance to primary road, meter † | <400 | 1.11 (0.33–3.71) | 0.87 | 1.07 (0.39–2.95) | 0.89 |
400–1000 | 1.15 (0.80–1.65) | 0.45 | 1.03 (0.69–1.55) | 0.87 | |
>1000 | Ref | --- | Ref | --- |
Abbreviations: OR = odds ratio; CI = confidence interval; Ref = reference category. * Adjusted for sex, age at enrollment (dichotomized by age 2 months), race/ethnicity, health insurance type, preterm birth (with cut-off at 37 months), median household income estimated by ZIP code at enrollment, parental history of asthma, population density of residential area at birth, and infant tobacco exposure at enrollment, and clustering by site. † Pooled estimates derived by weighting exposures according to duration spent each address up to age three or time outcome occurred, whichever happened first.