Table 4.
Test parameters for individual ATGs for a subgroup of symptomatic patients (estimates and 95% confidence intervals).
| Ecotest | JoysBio | ND COVID | Standard Q | VIVADiag | ||
|---|---|---|---|---|---|---|
| N/POSPCR/POSPCR+V | 134/86/73 | 132/76/50 | 99/58/50 | 66/33/24 | 152/73/40 | |
| PCR | Prevalence | 64.2 (55.4–72.3) | 57.6 (48.7–66.1) | 58.6 (48.2–68.4) | 50.0 (37.4–62.6) | 48.0 (39.9–56.3) |
| Sensitivity | 83.7 (74.2–90.8) | 60.5 (48.6–71.6) | 77.6 (64.7–87.5) | 63.6 (45.1–79.6) | 46.6 (34.8–58.6) | |
| Specificity | 95.8 (85.7–99.5) | 96.4 (87.7–99.6) | 56.1 (39.7–71.5) | 97 (84.2–99.9) | 97.5 (91.2–99.7) | |
| PPV | 97.3 (90.6–99.7) | 95.8 (85.7–99.5) | 71.4 (58.7–82.1) | 95.5 (77.2–99.9) | 94.4 (81.3–99.3) | |
| NPV | 76.7 (64.0–86.6) | 64.3 (53.1–74.4) | 63.9 (46.2–79.2) | 72.7 (57.2–85) | 66.4 (57–74.9) | |
| PCR + viability | Prevalence | 54.5 (45.7–63.1) | 37.9 (29.6–46.7) | 50.5 (40.3–60.7) | 36.4 (24.9–49.1) | 26.3 (19.5–34.1) |
| Sensitivity | 98.6 (92.6–100.0) | 92 (80.8–97.8) | 90 (78.2–96.7) | 87.5 (67.6–97.3) | 85.0 (70.2–94.3) | |
| Specificity | 96.7 (88.7–99.6) | 97.6 (91.5–99.7) | 63.3 (48.3–76.6) | 97.6 (87.4–99.9) | 98.2 (93.7–99.8) | |
| PPV | 97.3 (90.6–99.7) | 95.8 (85.7–99.5) | 71.4 (58.7–82.1) | 95.5 (77.2–99.9) | 94.4 (81.3–99.3) | |
| NPV | 98.3 (91.1–100.0) | 95.2 (88.3–98.7) | 86.1 (70.5–95.3) | 93.2 (81.3–98.6) | 94.8 (89.1–98.1) | |
N—number of patients in the group; POSPCR—number of positive patients acc. to RT-PCR; POSPCR+V—number of positive patients according to the combined RT-PCR+viability endpoint; PPV—positive predictive value; NPV—negative predictive value.