Table 1.
Low-dose rATG induction ≤ 4.5 mg/kg (n = 83) | Standard-dose rATG induction > 4.5 mg/kg (n = 152) | P value | |
---|---|---|---|
Age (mean), yr | 13 | 12.1 | 0.2 |
Sex (male), % | 62.7 | 61.2 | 0.83 |
Race, % | 0.18 | ||
White | 57 | 47 | |
Black | 26 | 38 | |
Other | 17 | 15 | |
Etiology of ESKD, % | 0.65 | ||
Obstructive uropathy/dysplasia | 38 | 39.5 | |
Focal segmental glomerulosclerosis | 16 | 14.5 | |
Other glomerular diseases | 7 | 13 | |
Unknown | 4 | 4 | |
Other | 35 | 29 | |
Transplant type (deceased), % | 56.8 | 66.2 | 0.36 |
PRA (mean ± standard error), % | |||
Class I | 4.5 ± 1.6 | 2.3 ± 1 | 0.26 |
% Subjects with class I PRA > 80% | 0 | 0 | |
Class II | 5.9 ± 1.7 | 2.1 ± 1.1 | 0.07 |
% Subjects with class II PRA > 80% | 0 | 0 | |
CMV risk, % | 0.52 | ||
High | 33 | 35 | |
Intermediate | 39 | 45 | |
Low | 28 | 20 | |
EBV risk, % | 0.29 | ||
High | 19 | 31 | |
Intermediate | 78 | 65 | |
Low | 3 | 4 |
CMV, cytomegalovirus; EBV, Epstein-Barr virus; ESKD, end-stage kidney disease; PRA, panel reactive antibody; rATG, rabbit antithymocyte globulin.