Table 2.
Distribution of laboratory test results before first treatment in the CKD stage 3, 4, and 5 cohorts
| Patients (n)b | Distribution of most recent laboratory test result before treatmenta |
|||||||
|---|---|---|---|---|---|---|---|---|
| Mean | SD | Min | Q1 | Median | Q3 | Max | ||
| Distribution of PTH (pg/ml) before first treatment with activated vitamin D compounds | ||||||||
| Stage 3 | 2163 | 153.7 | 115.8 | 1.0 | 90.5 | 125.0 | 185.0 | 1528 |
| Stage 4 | 2016 | 221.0 | 164.5 | 3.0 | 128.0 | 182.0 | 267.0 | 2541 |
| Stage 5 | 379 | 351.8 | 261.0 | 10.0 | 167.0 | 283.0 | 446.1 | 2072 |
| Distribution of 25D (ng/ml) before first treatment with nutritional vitamin D (25D) | ||||||||
| Stage 3 | 12,422 | 24.3 | 14.0 | 1.0 | 14.0 | 22.0 | 31.0 | 150 |
| Stage 4 | 2620 | 22.4 | 13.3 | 1.0 | 12.8 | 20.0 | 29.0 | 110.2 |
| Stage 5 | 286 | 20.9 | 13.1 | 2.6 | 11.8 | 18.0 | 27.0 | 75.0 |
| Distribution of phosphorus (mg/dl) before first treatment with oral phosphate binder | ||||||||
| Stage 3 | 8042 | 3.6 | 1.2 | 1.5 | 2.9 | 3.4 | 4.0 | 13.2 |
| Stage 4 | 3026 | 4.6 | 1.6 | 1.5 | 3.5 | 4.3 | 5.6 | 13.7 |
| Stage 5 | 831 | 5.8 | 1.6 | 1.6 | 4.8 | 5.7 | 6.6 | 15.7 |
CKD, chronic kidney disease; Max, maximum; Min, minimum; PTH, parathyroid hormone.
a
Among treatment-naive patients.
b
Distributions were calculated among patients who had no prior history of treatment (i.e., before the index date of the given CKD stage). Laboratory test results were considered only if the test occurred on or after the index date and before or on the date of first treatment.